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But these aren't approved medical uses

Fluoride in Drinking Water House Bill 103 would allow officials at local water systems to opt out of adding fluoride to their water supply

Jan 5 2019;393(10166):31-39

(2008) (R)-8-(3-Amino-Piperidin-1-Yl)-7-But-2-Ynyl-3-Methyl-1-(4-Methyl-Quinazolin-2-Ylmethyl)-3,7-Dihydro-Purine-2,6-Dione (BI 1356), a Novel Xanthine-Based Dipeptidyl Peptidase 4 Inhibitor, has a Superior Potency and Longer Duration of Action Compared with Other Dipeptidyl Peptidase-4 Inhibitors

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Lancet 395 , 142155 (2020)